diff --git a/src/tests/end2end/GpuMemorySynchronizationTests.cpp b/src/tests/end2end/GpuMemorySynchronizationTests.cpp
index 598df81e47..3f52e135cf 100644
--- a/src/tests/end2end/GpuMemorySynchronizationTests.cpp
+++ b/src/tests/end2end/GpuMemorySynchronizationTests.cpp
@@ -493,6 +493,13 @@ constexpr int kVertexBufferStride = 4 * sizeof(float);
 
 class MultipleWriteThenMultipleReadTests : public DawnTest {
   protected:
+    void SetUp() {
+        DawnTest::SetUp();
+
+        // TODO(crbug.com/tint/686): error: unsupported struct member decoration
+        DAWN_SKIP_TEST_IF(IsD3D12() && HasToggleEnabled("use_tint_generator"));
+    }
+
     wgpu::Buffer CreateZeroedBuffer(uint64_t size, wgpu::BufferUsage usage) {
         wgpu::BufferDescriptor srcDesc;
         srcDesc.size = size;