diff --git a/src/dawn/native/Device.cpp b/src/dawn/native/Device.cpp
index a4e2e1746c..be870c6d20 100644
--- a/src/dawn/native/Device.cpp
+++ b/src/dawn/native/Device.cpp
@@ -618,7 +618,7 @@ BlobCache* DeviceBase::GetBlobCache() {
     // TODO(crbug.com/dawn/1481): Shader caching currently has a dependency on the WGSL writer to
     // generate cache keys. We can lift the dependency once we also cache frontend parsing,
     // transformations, and reflection.
-    if (IsToggleEnabled(Toggle::EnableBlobCache)) {
+    if (IsToggleEnabled(Toggle::EnableBlobCache) && !IsToggleEnabled(Toggle::DisableBlobCache)) {
         return mAdapter->GetInstance()->GetBlobCache();
     }
 #endif
diff --git a/src/dawn/native/Toggles.cpp b/src/dawn/native/Toggles.cpp
index ebee065e05..20e44f506b 100644
--- a/src/dawn/native/Toggles.cpp
+++ b/src/dawn/native/Toggles.cpp
@@ -261,6 +261,12 @@ static constexpr ToggleEnumAndInfoList kToggleNameAndInfoList = {{
       "mips (level >= 2) doesn't work correctly. Workaround this issue by detecting this case and "
       "rendering to a temporary texture instead (with copies before and after if needed).",
       "https://crbug.com/dawn/1071"}},
+    {Toggle::DisableBlobCache,
+     {"disable_blob_cache",
+      "Disables usage of the blob cache (backed by the platform cache if set/passed). Prevents any "
+      "persistent caching capabilities, i.e. pipeline caching.",
+      "https://crbug.com/dawn/549"}},
+    // TODO(dawn:549) Remove after deprecating usage on the Chromium side.
     {Toggle::EnableBlobCache,
      {"enable_blob_cache",
       "Enables usage of the blob cache (backed by the platform cache if set/passed). Necessary for "
diff --git a/src/dawn/native/Toggles.h b/src/dawn/native/Toggles.h
index 5a29de3955..3dde2e4186 100644
--- a/src/dawn/native/Toggles.h
+++ b/src/dawn/native/Toggles.h
@@ -72,6 +72,7 @@ enum class Toggle {
     VulkanUseZeroInitializeWorkgroupMemoryExtension,
     D3D12SplitBufferTextureCopyForRowsPerImagePaddings,
     MetalRenderR8RG8UnormSmallMipToTempTexture,
+    DisableBlobCache,
     EnableBlobCache,
     D3D12ForceClearCopyableDepthStencilTextureOnCreation,
     D3D12DontSetClearValueOnDepthTextureCreation,