diff --git a/src/dawn/fuzzers/DawnWireServerFuzzer.cpp b/src/dawn/fuzzers/DawnWireServerFuzzer.cpp
index ae2bb91860..d1c1f2c6c5 100644
--- a/src/dawn/fuzzers/DawnWireServerFuzzer.cpp
+++ b/src/dawn/fuzzers/DawnWireServerFuzzer.cpp
@@ -19,6 +19,7 @@
 #include <vector>
 
 #include "dawn/common/Assert.h"
+#include "dawn/common/DynamicLib.h"
 #include "dawn/common/Log.h"
 #include "dawn/common/SystemUtils.h"
 #include "dawn/dawn_proc.h"
@@ -49,6 +50,9 @@ class DevNull : public dawn::wire::CommandSerializer {
 
 std::unique_ptr<dawn::native::Instance> sInstance;
 static bool (*sAdapterSupported)(const dawn::native::Adapter&) = nullptr;
+#if DAWN_PLATFORM_IS(WINDOWS) && defined(ADDRESS_SANITIZER)
+static DynamicLib sVulkanLoader;
+#endif
 
 }  // namespace
 
@@ -57,6 +61,15 @@ int DawnWireServerFuzzer::Initialize(int* argc, char*** argv) {
     // Swiftshader crashes libFuzzer. When this is fixed, move this into Run so that error injection
     // for adapter discovery can be fuzzed.
     sInstance = std::make_unique<dawn::native::Instance>();
+
+    // TODO(crbug.com/1038952): Although we keep a static instance, when discovering default Vulkan
+    // adapters, if no adapter is found, the vulkan loader DLL will be loaded and then unloaded,
+    // resulting in ASAN false positives. We work around this by explicitly loading the loader
+    // without unloading it here.
+#if DAWN_PLATFORM_IS(WINDOWS) && defined(ADDRESS_SANITIZER)
+    sVulkanLoader.Open(GetExecutableDirectory().value_or("") + "vulkan-1.dll");
+#endif
+
     sInstance->DiscoverDefaultAdapters();
 
     return 0;